A critical role of TAK1 in B-cell receptor–mediated nuclear factor κB activation
نویسندگان
چکیده
منابع مشابه
Negative role of TAK1 in marginal zone B-cell development incidental to NF-κB noncanonical pathway activation
The transcription factor nuclear factor-κB (NF-κB) signaling pathway is crucial in B-cell physiology. One key molecule regulating this pathway is the serine/threonine kinase TAK1 (MAP3K7). TAK1 is responsible for positive feedback mechanisms in B-cell receptor signaling that serve as an NF-κB activation threshold. This study aimed to better understand the correlation between TAK1-mediated signa...
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ژورنال
عنوان ژورنال: Blood
سال: 2009
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2008-08-176057